Product Info Summary
SKU: | A05148 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, IHC-P, WB, IF (paraffin) |
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Product info
Product Name
Anti-Ras-related protein Rab-5C RAB5C Antibody
SKU/Catalog Number
A05148
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Ras-related protein Rab-5C RAB5C Antibody (Catalog# A05148). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Ras-related protein Rab-5C RAB5C Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05148)
Host
Rabbit
Contents
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
7A7
Isotype
Rabbit IgG
Immunogen
A peptide derived from human RAB5C. Immunogen sequence location: 122 - 171
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A05148 is reactive to RAB5C in Human, Mouse, Rat
Applications
A05148 is guaranteed for ELISA, IHC-P, WB, IF (paraffin) Boster Guarantee
Observed Molecular Weight
72 kDa
Calculated molecular weight
23.483kDa
Background of RAB5C
Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western Blot, 1:500 - 1:2000
Immunohistochemistry, 1:100 - 1:300
ELISA, 1:5000
Not yet tested in other applications.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of lysates from LOVO, HeLa, and Jurkat cells, using RAB5C Antibody. The lane on the right is blocked with the synthesized peptide.
Protein Target Info & Infographic
Gene/Protein Information For RAB5C (Source: Uniprot.org, NCBI)
Gene Name
RAB5C
Full Name
Ras-related protein Rab-5C
Weight
23.483kDa
Superfamily
small GTPase superfamily
Alternative Names
L1880; MGC117217; RAB5C, member of RAS oncogene family; RAB5C, member RAS oncogene family; RAB5CL; RAB5L; RABLMGC138857; ras-related protein Rab-5C RAB5C L1880L, RAB5L, RABL, RAB5C RAB5C, member RAS oncogene family ras-related protein Rab-5C|RAB5C, member of RAS oncogene family
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on RAB5C, check out the RAB5C Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for RAB5C: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ras-related protein Rab-5C RAB5C Antibody (A05148)
Hello CJ!
No publications found for A05148
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Customer Reviews
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Customer Q&As
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1 Customer Q&As for Anti-Ras-related protein Rab-5C RAB5C Antibody
Question
We are currently using anti-RAB5C antibody A05148 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on horse tissues as well?
Verified Customer
Verified customer
Asked: 2019-05-21
Answer
The anti-RAB5C antibody (A05148) has not been tested for cross reactivity specifically with horse tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.
Boster Scientific Support
Answered: 2019-05-21